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Mesothelioma and Non Asbestos Exposure Mesothelioma most commonly develops in the lung lining (pleura) and abdomen (peritoneum). This rare cancer may develop in the linings of the heart or testes (pericardium). Asbestos is the most significant risk factor for mesothelioma. However, some people diagnosed with mesothelioma may not have any history of asbestos exposure. Exposure to Asbestos Asbestos is a natural mineral that was previously used in industrial and construction products all over the world. Workers in asbestos-related industries handled the material on a daily basis and were at risk of exposure. Asbestos fibres can lodge in the lungs and cause lung disease. This is called asbestosis. As time passes the trapped fibers may cause mesothelioma as well. Asbestos is also inhaled or consumed, and the risk of developing mesothelioma and other asbestos-related diseases rises with the length and quantity of exposure. Most cases of mesothelioma stem from exposure to occupational toxins. Asbestos was employed in various trades, including construction, insulation and electrical work, as well as automobile maintenance and pipefitting. As these trades are dominated by males, 75-80% percent of mesothelioma patients are men. However, the gradual elimination of asbestos in the United States and other first-world countries has decreased on-the-job exposure. This has resulted in a shift of cases and asbestos exposure in non-occupational settings increasing in frequency. Non-occupational Mesothelioma can be caused by asbestos is released at the workplace or found at the home or in schools. It can also be caused by secondhand exposure for example, when a family member handles the work clothes of an exposed asbestos worker. Those who experience this type of exposure may have symptoms such as breathlessness or chest pain that is commonly mistaken for heart or lung conditions. Some studies have found that non-occupational exposure is linked to mesothelioma, but the results are inconsistent. A majority of these studies were conducted on a limited sample size, and between-study the degree of heterogeneity is high. It is imperative to conduct additional studies to confirm the connection between non-occupational asbestos exposure and mesothelioma. Those who have been exposed to asbestos in non-occupational settings should speak with their doctor regarding their asbestos-related background. They should have mesothelioma screening in the event of concerns and request the referral to a specialist. Specialists in mesothelioma can provide the best treatment and treatment to improve a patient's chances of survival. They will analyze medical records and perform imaging tests to determine if mesothelioma is present. They will also provide advice on how to file mesothelioma lawsuits to receive compensation from an asbestos trust funds. Secondhand Exposure While asbestos exposure is the primary cause of mesothelioma not the only way to get this cancer. In fact, there is only a tiny amount of evidence that suggests that people may develop mesothelioma despite not having directly handled asbestos or worked in an industry that involved asbestos-related activities. This is known as secondary or non-occupational asbestos exposure. Asbestos fibers are extremely small and they can stick to hair, clothing skin, and other surfaces. Workers may carry dangerous fibers in their work clothes at home and then pass them on to family members. These stray asbestos fibers can be swallowed or inhaled which can lead to mesothelioma. This mesothelioma type occurs more often among women and typically in the lungs. However, it can also be found in the abdomen or chest wall. The most common symptom is shortness of breath (dyspnea) and it can be coupled with other signs like fluid in the lungs or a swelling in the scrotum. The mesothelioma that develops in the lungs is referred to as mesothelioma of the pleural region. Mesothelioma that is affecting the chest wall, stomach, or is referred to as peritoneal mesothelioma. This type of mesothelioma can cause a number of symptoms, including abdominal pain, difficulty in breathing and constipation. Several studies have reported that individuals with no background of occupational exposure to asbestos may develop mesothelioma as a result of exposure to harmful fibers. The people who were affected typically resided with someone who was exposed to asbestos. They might have worn the clothing of an asbestos worker or had other contact. Veterans are at a high risk of developing mesothelioma due to asbestos that was used extensively in military bases vessels, vehicles and bases. The Navy is at a greater risk, as asbestos was employed in the hull and gun turrets of ships to shield them from fire. Asbestos was also often taken home by sailors after their work on ships that were contaminated. Environmental Exposure Mesothelioma has been linked to various substances. Nevertheless, the disease is often linked to exposure to asbestos. Asbestos is a naturally occurring mineral that was used for a variety of years in manufacturing. The mineral is heat resistant and tough, which makes it ideal for insulation, brakes, shingles flooring, and many other products. When asbestos is broken up, it creates dust that can be breathed in or swallowed. These fibers can stay in the stomach and lungs for many years, triggering symptoms of mesothelioma. The most common mesothelioma symptoms are difficulty breathing, abdominal pain, and chest pain. Asbestos exposure can cause these symptoms to last for up to 60 years. It is crucial to speak with an expert physician if you experience these symptoms. Telling your doctor about asbestos exposure is important. This can help avoid a false diagnosis and ensure that you receive the proper treatment. Mesothelioma that is caused by exposure to asbestos is most frequent in those who have worked directly with the substance however, it can also affect loved people who were exposed. This is referred to as secondary exposure. Family members may inhale or ingest asbestos fibers from the work footwear, clothing, or tools. These particles can also be brought to home by someone who is wearing or having their hair. It is for this reason that mesothelioma sufferers as well as their families must always wash their clothes in a clean manner after working with asbestos. There is a large body of literature that shows an association between exposure to nonasbestos and mesothelioma. However there aren't any definitive conclusions yet on the role of other agents. For example there is evidence that the zeolites erionite and chrysotile can cause mesothelioma. Erionite is found in soil and rocks from certain areas in Turkey where the risk of mesothelioma in the pleural cavity is high. mission asbestos attorney on the connection between asbestos and mesothelioma is in progress. Funnel plots indicate the possibility of bias in publications and there is a large level of heterogeneity between studies. However, it is still clear that asbestos exposure from work is the most significant risk factor for mesothelioma. Genetics Mesothelioma is a rare disease caused by malignant mesothelial cells which develop out of control and invade surrounding tissues. It is also able to spread throughout the body via the lymphatic or blood system, which can affect other organs. While asbestos is the main cause of mesothelioma, it is not the sole risk factor. The condition may be triggered by other genetic and environmental factors. In some cases, mesothelioma has occurred in people who had no direct exposure to asbestos. They are known as mesothelioma victims who are not employed. They were usually exposed indirectly by the handling of harmful household items or clothing by anyone who was exposed to asbestos in their home. It is possible to be diagnosed with mesothelioma following inhaling asbestos fibers from clothing of a family member. Studies have shown that these kinds of mesothelioma cases are more likely to have longer periods of latency and are more likely to be diagnosed in wives than in husbands. Scientists are examining the possibility that mesothelioma-related genetic predispositions could play a role in the development. Recent studies have shown the mutation of the gene BAP1 increases the risk of mesothelioma among asbestos-exposed patients. This is significant because it could lead improved screening procedures for people who are at risk of developing mesothelioma. Researchers have identified a variety of genes that are associated with mesothelioma. These genes are usually mutated in mesothelioma, and they suppress tumor growth. These genes include large tumor suppressor 2 (LATS2), and NF2. People with mesothelioma in their family are at greater chance of contracting the disease. This is due to certain genes, including BAP1 BAP1 one, can be inherited from an individual parent. Asbestos was used heavily in the military for a number of years and veterans have the highest rates of mesothelioma compared to other occupational groups. Those who served in the Navy and on ships specifically were at risk the most because of the extensive exposure to asbestos in insulation, fireproofing materials, and shipbuilding.